Greetings from the Chair of the 28th Annual Meeting of the Japanese Society for Alternatives to Animal Experiments

We are pleased to announce that the 28th Annual Meeting of the Japanese Society for Alternatives to Animal Experiments will be held from December 10th (Thu) to 12th (Sat), 2015 at Workpia Yokohama (24-1, Yamashita-cho, Yokohama-shi, Kanakaga, http://workpia.or.jp/).

The Japanese Society for Alternatives to Animal Experiments (JSAAE) is a scientific organization that undertakes research, development, education, and surveillance activities for promoting international acceptance of the Three Rs (Replacement, Reduction and Refinement) as guiding principles for the proper use of animals in scientific testing（http://www.asas.or.jp/jsaae/outline/index.html）.

Since many animals are used to evaluate biological safety of chemicals to human, development of alternative methods to animal testing is one of the important missions of JSAAE. For development of a new test guideline, it is necessary to conduct a validation study to confirm transferability, reproducibility and predictivity of the test developed according to the OECD guidance on new test validation issued in 2005. Therefore, development of a new test guideline is not easy. In this situation, development of alternative methods was accelerated　by the 7th amendment of EU Cosmetic Directive, and alternatives of local toxicity such as eye and skin irritation tests and skin sensitization test were developed. In Japan, many validation studies were performed with cooperation of JaCVAM (Japanese　Center　for　the　Validation　of　Alternative　Methods) and some of them have been adopted to OECD test guidelines.

In the 28th annual meeting, we planned several sessions. Firstly, they are two sessions to introduce the present situation of international validation studies on alternative test methods (sensitization and irritation tests) conducted in Japan. Secondary, we planned a special lecture by Dr. Jun Kanno (Division of Cellular & Molecular Toxicology, Biological Safety Research Center, National Institute of Health Sciences), the title is “Current Problems and Perspectives of the Alternate Test Methods from the Viewpoint of in vivo Toxicology”. He will lecture about alternative test methods from the point of view of a specialist of in vivo toxicology. Since there is more difficulty in development of the alternative test method of general toxicity than current situation, we want to provide opportunity of discussion about future alternatives of general toxicity in this session.

Moreover, five speakers will talk about ES/iPS cells and tissue engineering methodologies because they can became useful tools for future development of alternatives. Current situation of alternative test methods indicates to be essential for animal tests to evaluate biological safety of chemicals. So, Dr. Tsutomu Miki Kurosawa who is a convener of the working group in ISO/TC194　Biological and Clinical Evaluation of Medical Devices will talk about international trend in animal welfare as a educational lecture. In addition to above sessions there are several sessions by Shiseido, Japan Chemical Industry Association, Mandom International Research Grants on Alternative to Animal Experiments, the committee of JSAAE and a luncheon seminar by Nippon Medical & Chemical Instruments.

The theme of the 28th annual meeting of JSAAE is “Let’s discuss current situation and future of alternative test methods”. We would like to provide opportunity to share information and discuss alternative test methods by gathering all participants on one floor. Since almost three hundred participants registered for this meeting, I hope participants are actively discussed during this meeting.

Finally, this meeting was supported by a lot of companies or organizations and was achieves by cooperation of speakers, chairs and members of management committee. I would like to thank everyone for their understanding and cooperation.

Japanese Society for Alternatives to Animal Experiments
The Chair of the Annual Meeting
Food Drug Safety Center, Hatano Research Institute
Kohji YAMAKAGE

Website: http://jsaae28.umin.jp/

Contact to
Secretariat of the 28th Annual Meeting of the Japanese Society for Alternatives to Animal Experiments Faculty of Hatano Research Institute, Food and Drug Safety Center
729-5, Ochiai, Hadano, Kanagawa, 257-8523, Japan
TEL：+81-463-82-4751
FAX：+81-463-82-9627
E-mail：jsaae-28@fdsc.or.jp

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（As of September 28, 2015）

• Timetable（PDF）
• Program（PDF）

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Poster presentations

All posters will be presented in the First Hall and the Second Hall throughout three days from Thursday, 10 December to Saturday, 12 December. Poster viewing is scheduled on Friday, 11 December.

Poster Dimensions

The poster boards will be 200 cm in height and 90 cm in width. However, please do not use l0 cm from the bottom, because it is hard to see. Refer to the right diagram (The diagram on the right can be viewed on the conference web site). Generally, please write the title, names and affiliations within 20 cm from the top.

The poster number will be affixed to a space 20 cm x 20 cm in the top left.

The width that may be used for the title is 70 cm. The poster number will be prepared by the conference office beforehand.

Poster Display

All posters will be presented in the First Hall and the Second Hall throughout three days from Thursday, 10 December to Saturday, 12 December. Poster viewing is scheduled on Friday, 11 December.

Location of posters:
The First Hall: P-01~P-26
The Second Hall: P-27~P57

Poster set-up time: Thursday, 10 December, 16:00 – Friday, 11 December, 9:00

Poster dismantling time: Saturday, 12 December, 14:20-15:00

• Each poster was assigned a number upon submission of the abstract and should be mounted on the board marked with the same number.
• Drawing pins for the posters and ribbons for the presenters will be prepared on the poster board.
• Depending upon the circumstances, if the dismantle time has passed, the poster will be removal by stuffs. Additionally, they will dispose of posters that are not taken after 18:00.

Presentations that excel will be awarded with a poster prize. After selection by the judges, notification of the winners as well as an awards ceremony will be performed during the closing ceremony on the Saturday, 12 December.

Poster explanation

Poster explanation: Friday, 11 December, 14:30 - 17:30

Poster explanation will be conducted according below;
14:30~15:30: Odd number (P1, P3, P5……..)
15:30~16:00: Free discussion
16:00~17:00: Even number (P2, P4, P6……..)
17:30~18:00: Free discussion

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Outline of the special lectures, educational lectures, and symposium lectures
[Speaking academics]

Windows 7/PC 1(64 bits) PCs with Office 2013 Standard (32 bits) have been prepared.

We cannot deal with compilation or any kind of audio output.

Receipt of projector data on the day

(1) Receipt of presentation data files and notebook PCs will be performed by an imaging/PC operator at the location of each presentation, so please bring these items at the presentation desk at least 90 minutes before the start of the lecture or symposium.

(2) We ask that presentation data be provided on USB flash memory or CD-R media. Please make sure you run a virus check on the media beforehand. We will take custody of the data after confirming that the presentation data works. Also, please set the file name to 'Session_Name#Speaker_Name', where '#' is the session number.
Example: Special_Iecture_****, Symposium#_**** (where '*' are half-width or full-width characters).

(3) Please convert data from non-Windows OS presentation software - for example, PowerPoint for Mac OS - into Windows PowerPoint-compatible files.
Due to such conversions, it might not be possible to reproduce the layout and style of the presentation; therefore, please check this beforehand and bring the presentation saved as a PDF file.

(4) While the presentation data will be momentarily saved onto the PCs at the conference, the office staff will be responsible for the disposal of any data held after the end of the conference.

Notes regarding bringing notebook pes

(1) Please prepare an adapter for the PC.

(2) The output cable connectors provided at the conference are usually standard Mini D-sub15 type, such as is equipped in most PCs. For some Mac PCs, a conversion connector may be necessary. Please bring this yourself.

(3) Please turn off screensavers and power-saving settings. Additionally, because it is sometimes difficult to display the PC screen when a second screen is set up, please confmn the settings beforehand.
Also, please be aware that those responsible for 'chairman/speaker reception' will not be able to deal with changing these settings.

(4) Please ensure you prepare for mishaps by bringing backup data on a USB drive or CD-R.

(5) Even if videos have identical file names, differences in directory organization and the encoding files often cause them not to play back as desired on the conference pes. Please be very cautious with the use of video files.

Please arrive 10 minutes before your lecture and wait in the seat reserved for the next speaker.

Please check for yourself how well the image is projected. A laser pointer will be provided at the podium; however, if you want a laser pointer with special features, please bring one.

After the special lectures are finished, there will be a ceremony for the presentation of a letter of thanks.

Please abide strictly to the lecture times. In the case of excessive run-over that does not stop after a time decided by the chairman, the lecture may be forced to end. We ask for your cooperation in this matter.

[Chairing academics]

Please be in the chairman's seat 10 minutes before each lecture.

The conference's progress is entrusted to the chairman. Please strictly observe the end times.

Lecture times differ by session; however, as a rule, please ring the bell once 3 minutes before the lecture, twice when the lecture is fmished, and 3 times when the time for questions is over.

Some preparation is necessary for the speakers to take the stage at the end, so please consult with them the day before.

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